Statement: Mindfulness-based therapies (e.g., Mindfulness Based Cognitive Therapy [MBCT] and Mindfulness Based Stress Reduction [MBSR]) could be used to reduce depressive symptoms in people with Major Depressive Disorder (Grade 2).

Recommendation Grade: 2

Strength of evidence: Limited; Grade B Acceptability: Good

Clinical recommendation was based on: 1 x meta-analysis (k=9, N=762)(Goldberg et al. 2018) Reported effect size: Moderate (Standard mean difference = 0.59)(Goldberg et al. 2018) Risk of Bias assessment: Low risk of bias meta-analysis of moderate risk of bias trials