Statement: Support regarding individualized interaction with green spaces or participation in a green space-focused program may be used to reduce depressive symptoms in people with Major Depressive Disorder

Recommendation Grade: 3

Strength of evidence: Low; Grade C1 Acceptability: Good

Clinical recommendation was based on: 2 randomized controlled trial and 2 non-randomized clinical trials (N=116 participants)(Barton et al. 2012; Berman et al. 2012; Korpela et al. 2016; Vujcic et al. 2017) Reported effect size: Small to Moderate (Eta squared 0.024–0.49) (Barton et al. 2012; Berman et al. 2012; Korpela et al. 2016; Vujcic et al. 2017) Risk of bias assessment: High ROB