Table 2.

Relative effect of an intensive lifestyle intervention on left atrium structural and functional parameters

	Control group		ILI group		Difference ILI vs. control
	Y3 vs. baseline	Y5 vs. baseline	Y3 vs. baseline	Y5 vs. baseline	Y3 vs. baseline	Y5 vs. baseline
LA emptying fraction	0.96 (0.94–0.99)	0.95 (0.93–0.98)	0.96 (0.93–0.98)	0.97 (0.94–1.00)	1.00 (0.96–1.03)	1.01 (0.97–1.05)
LA longitudinal strain	0.88 (0.85–0.92)	0.82 (0.79–0.85)	0.91 (0.88–0.95)	0.85 (0.82–0.89)	1.04 (0.98–1.09)	1.04 (0.98–1.10)
Indexed LA volume	1.07 (1.03–1.11)	1.19 (1.15–1.23)	1.09 (1.05–1.13)	1.18 (1.14–1.23)	1.02 (0.97–1.07)	0.99 (0.94–1.05)
LA maximum volume	1.07 (1.03–1.11)	1.19 (1.14–1.23)	1.07 (1.03–1.11)	1.16 (1.12–1.20)	1.00 (0.95–1.05)	0.98 (0.93–1.03)
LA conduit strain	0.88 (0.82–0.93)	0.84 (0.79–0.89)	0.91 (0.86–0.97)	0.82 (0.77–0.87)	1.04 (0.95–1.13)	0.98 (0.90–1.06)
LA pump strain	0.92 (0.87–0.97)	0.84 (0.79–0.89)	0.92 (0.87–0.97)	0.88 (0.83–0.93)	1.01 (0.93–1.09)	1.05 (0.97–1.13)
LA stiffness index	1.11 (1.05–1.17)	1.17 (1.11–1.23)	1.07 (1.02–1.13)	1.10 (1.04–1.16)	0.97 (0.90–1.04)	0.94 (0.87–1.02)
LA function index	0.89 (0.84–0.94)	0.82 (0.78–0.87)	0.88 (0.83–0.93)	0.82 (0.78–0.87)	0.99 (0.92–1.07)	1.00 (0.92–1.08)

Before using the mixed models, the variables were log-transformed. Later, they were back-transformed to enable easier interpretation. In this table, the values represent the ratios of geometric means, alongside their 95% CI. The models were adjusted for the recruitment centre.

LA, left atrial.