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Figure 10. The downstream molecular mechanisms of IQGAP3 in U251 cells. (A) The mRNA expression levels of IQGAP3 PLK1, PI3K, AKT in shNC and shIQGAP3 groups of U251 cells. (B) The relative protein expression levels of IQGAP3 PLK1, PI3K, p-PI3K, AKT and p-AKT in shNC and shIQGAP3 groups of U251 cells. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.