Figure 8. Anti-glioma small molecule drugs targeting IQGAP3. (A) Promising compounds against gliomas were screened by the CMap platform, and the heatmap shows the top 10 negatively correlated small molecules, with blue indicating negative correlation and red indicating positive correlation. (B) The results of molecular docking simulations of IQGAP3 with compound BRD-K88742110. (C) The results of molecular docking simulations of IQGAP3 with compound LY-303511. Solid blue lines indicate hydrogen-bonded hydrophilic interactions and dashed lines indicate hydrophobic interactions.
