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| Sr. No. | Hub gene | Drug name | Effect | Reference | Group |
|---|---|---|---|---|---|
| 1 | MMP2 | Alvocidib | Decrease expression of MMP2 mRNA | A20630 | Approved |
| Estradiol | A21152 | ||||
| 2 | MMP9 | Capsaicin | Decrease expression of I MMP9 mRNA | A21513 | Approved |
| Dronabinol | A22085 | ||||
| 3 | MMP12 | Acetaminophen | Decrease expression of MMP12 mRNA | A20420 | Approved |
| 4 | MMP16 | Estradiol | Decrease expression of MMP16 mRNA | A21179 | Approved |
