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. 2024 Mar 20;32(4):785–797. doi: 10.32604/or.2024.047021

Table 2. Genetic association models of CYP2B6*9 (G516T) variant and the risk of B-CLL.

CYP2B6*9 (G516T) B-CLL n (%) Control n (%) p-value OR (95% CI)
n % n %
Genotypes GG 41.0 41% 79.0 79% Reference
GT 39.0 39% 18.0 18% <0.001* 4.2 1.9– 9.3
TT 20.0 20% 3.0 3% <0.001* 12.8 3.5–45.6
Dominant model GG 41.0 41% 79.0 79% Reference
GT + TT 59.0 59% 21.0 21% <0.001* 5.4 2.8–10
Recessive model GG + GT 80.0 80% 97.0 97% Reference
TT 20.0 20% 3.0 3% <0.001* 8.1 2.2–28.3
Allelic model G 128.0 64% 188.0 94% Reference
T 72.0 36% 12.0 6% <0.001* 4.8 2.8–7.9

Note: Chi-square test was applied. OR: Odds ratio, CI: Confidence Interval, *: Statistically significant (if p < 0.05).