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. 2024 Mar 25;11(3):ENEURO.0399-23.2024. doi: 10.1523/ENEURO.0399-23.2024

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Copyright © 2024 Baravalle and Canavier

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 6. — Hyperpolarizing inhibition is more robust to noise than shunting inhibition for all values of coupling and external current. A, Bifurcation in the full 3D parameter space for hyperpolarizing (blue) and shunting (magenta) inhibition. B, SPO for hyperpolarizing inhibition. Peak conductance is 66 nS. B1, ISI histogram. B2. Spike time histogram. B3, Raster plot (down-sampled). B4, Membrane potential of a representative neuron. C, SPO for shunting inhibition. Peak conductance is 412.5 nS. C1, ISI histogram. C2, Spike time histogram. C3, Raster plot (down-sampled). C4. Membrane potential of a representative neuron. In both cases the noise intensity is 0.16 pA and bias current is 0.5 nA. Red dashed lines indicate the synaptic reversal potential.