Table 4.
Side effect profile by type of antiobesity medication
| Characteristic, N (%) | Celiac disease + AOM N=39 | AOM N=78 | p value |
|---|---|---|---|
| Any side effect | 12 (30.7) | 22 (28.2) | 0.83 |
| GI side effects* | 8 (66.7) | 12 (54.5) | 0.71 |
| Non-GI side effects¶ | 4 (33.3) | 10 (45.5) | 0.71 |
| Injectable GLP-1 receptor agonists | |||
| Any side effect | 7 (33.3) | 15 (35.7) | 1.00 |
| GI side effects | 6 (85.7) | 11 (73.3) | 1.00 |
| Non-GI side effects | 1 (14.3) | 4 (26.7) | 1.00 |
| Oral non-GLP-1 AOMs | |||
| Any side effect | 5 (27.8) | 7 (19.4) | 0.51 |
| GI side effects | 2 (40.0) | 1 (14.3) | 0.52 |
| Non-GI side effects | 3 (60.0) | 8 (85.7) | 0.52 |
Gastrointestinal symptoms included nausea/vomiting, abdominal pain, heartburn, diarrhea, and constipation.
Non-GI symptoms included dry mouth, fatigue, anxiety, insomnia, paresthesias, blurry vision and skin reaction.
AOM indicates antiobesity medication; GLP-1, glucagon-like peptide 1.