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. 2024 Mar 6;27(4):109433. doi: 10.1016/j.isci.2024.109433

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This is an open access article under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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APOBEC3A/B TC hotspots statistics of protein-coding transcripts of Pteropus alecto genome

(A) CDUR analysis on the bat genome shows two dense regions at the top-left and right-bottom extremes and relatively sparse dispersion elsewhere as in the human genome.

(B) Bat orthologs of human cancer and non-cancer genes show distinct distribution in mutational susceptibility but not in motif under-representation and (Kolmogorov-Smirnov test for motif-representation axis, P = 0.1701; for mutational susceptibility axis, P = 3.169 x 10^-5).