Table 3.
Clinical features of patients managed with fertility-sparing surgery treatment of ETT in the literature.
| Author | Patient No. | Age, years | Ethnicity | Gravida | Parity | Symptoms | Preceding pregnancy | Interval from last pregnancy, months | Pretreatment hCG, mIU/mL | FIGO stage | Mass features | Treatment | Overall outcome | Fertility outcome | Interval from remission to next pregnancy | Recurrence | Survival, months |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Liu W et al. (8) | 1 | NA | Asia, Chinese | NA | I | NA | Abdominal removal of uterine lesions + multi-agent chemotherapy | Remission | One of them had term birth by CS | NA | – | NA | |||||
| 2 | NA | ||||||||||||||||
| 3 | NA | Asia, Chinese | NA | I | NA | Hysteroscopic lesionectomy + multi-agent chemotherapy | Remission | NA | – | NA | |||||||
| 4 | 19 | Asia, Chinese | 2 | 1 | Vaginal spotting | Induced abortion | 24 | 100 | I | 2.4 × 1.6 × 1.4 cm in uterine cavity | D&C + hysteroscopic lesionectomy + 3 cycles of EMA-EP | Remission | A first-trimester miscarriage | NA | – | ≥20 | |
| Tse K Y et al. (28) | 5 | 25 | Asia, Chinese | 1 | 0 | Abdominal pain | Abortion | 21 | NA | I | 11.9 × 10.4 × 8.5 cm over the posterior uterine serosa | Laparoscopic removal of posterior uterine cyst | Remission | 2 full-term births (1 CS and 1 vaginal delivery) | 4 and 7.5 years | – | 89 |
| Davis M R et al. (29) | 6 | 31 | NA | 1 | 0 | VB | partial HM | 24 | 150,000 | I | <1 cm in uterus | D&C | Progressive disease (lung metastasis after 26 months) | NA | / | + | NA |
| 7 | 31 | NA | 0 | 0 | None | An undocumented spontaneous abortion | NA | <2 | NA (peritoneum metastasis) | <3 cm in uterus | Laparoscopic myomectomy and morcellation + EMA-EP | Stable disease (uterus and cervix recurrence after 26 months) | Spontaneous abortion | NA | + | NA | |
| Fang FY et al. (30) | 8 | 28 | NA | 1 | 1 | Abdominal pain, heavy VB | TPY | NA | 2,259–2,764 | I | 7.0 × 7.0 × 6.0 cm in the right cornual area of uterus | Laparoscopic lesionectomy and uterine repair | Remission | NA | / | – | NA |
| Zhang et al. (31) | 9 | 42 | Asia, Chinese | NA | NA | Irregular VB | HM | 36 | 96 | II | 2.0 ×2.0 × 2.0 cm in the right broad ligament of uterus | Lesionectomy | Remission | NA | / | – | 28 |
VB, vaginal bleeding; TPY, term pregnancy; HM, hydatidiform mole; CS, caesarean section.
+ positive; - negative; NA not available; / blank.