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. 2024 Mar 14;15:1342647. doi: 10.3389/fimmu.2024.1342647

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Copyright © 2024 Li, Zhang, Niu, Wu, Deng and Zhou

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The cellular interactions between components in TME. In the CXCL signaling pattern, the interaction between antigen presenting cells (macrophage, monocytes, cDC and pDC) and other components in TME of CTL group (A) or MSA2 group (B). (C–H) The plots illuminate, in each intriguing signaling pattern, the intercellular interactions circled T cells. (I–N) The plots indicate, in the realms of each interesting signaling, the interaction strength of each cellular communication centered on T cells. The thickness of each line infers the interaction strength.