Table 2.
Preoperative variables of patients who underwent oral cancer resection with flap reconstruction and did and did not have recipient-site surgical site infection (SSI)
| Variable | Without AEs (n = 64) | With AEs (n = 56) | p-value |
|---|---|---|---|
| Age (years), median (range) | 64 (30–86) | 63 (26–80) | 0.634a |
| Sex | |||
| Male | 50 (78.1%) | 35 (62.5%) | 0.072b |
| Female | 14 (21.9%) | 21 (37.5%) | |
| Low SMI | 6 (9.4%) | 14 (25.0%) | 0.028b |
| BMI (kg/m2), mean ± SD | 22.9 ± 4.1 | 21.8 ± 3.7 | 0.136a |
| Low BMI < 18.5 | 9 (14.1%) | 8 (14.3%) | 1.000b |
| Stage | |||
| II, III | 15 (23.4%) | 15 (26.8%) | 0.679b |
| IV | 49 (76.6%) | 41 (73.2%) | |
| Alcohol | 35 (54.7%) | 23 (41.1%) | 0.707b |
| Smoking | 33 (51.6%) | 27 (48.2%) | 0.855b |
| Location | |||
| Tongue | 40 (62.5%) | 29 (51.8%) | 0.150b |
| Mandible | 9 (14.1%) | 17 (30.4%) | |
| Buccal mucosa | 5 (7.81%) | 5 (8.93%) | |
| Floor of mouth | 10 (15.6%) | 5 (8.93%) | |
| Neck dissection | |||
| Unilateral | 53 (82.8%) | 47 (83.9%) | 1.00b |
| Bilateral | 11 (17.2%) | 9 (16.1%) | |
| ASA-PS score ≥ 2 | 27 (42.1%) | 21 (37.5%) | 0.709b |
| ACE-27 | |||
| 0–1 | 26 (40.6%) | 17 (30.4%) | 0.259b |
| 2–3 | 38 (59.4%) | 39 (69.6%) | |
| Preoperative laboratory data, median (IQR) | |||
| Leukocyte count (× 109/l) | 6.1 (5.2–8.0) | 6.2 (5.0–7.5) | 0.582a |
| Platelet count (× 109/l) | 235 (202–275) | 240 (193–285) | 0.807a |
| Hemoglobin (g/dl) | 14.5 (14.1–14.8) | 14.4 (14.0–14.7) | 0.356a |
| Albumin (g/dl) | 4.4 (4.1–4.6) | 4.4 (4.1–5.3) | 0.513a |
| C-reactive protein | 0.09 (0.05–0.28) | 0.075 (0.05–0.26) | 0.475a |
| Prognostic nutritional index | 51.3 (48.4–55.3) | 52.6 (48.9–55.9) | 0.566a |
| Operation time (min), median (IQR) | 783 (688–873) | 812 (668–857) | 0.816a |
| Blood loss (ml), median (IQR) | 670 (420–1027) | 670 (450–950) | 0.924a |
AE adverse event, ASA-PS American Society of Anesthesiologists physical status, BMI body mass index, IQR interquartile range, SMI skeletal muscle index