TABLE 2.

Viral titers in tissues following infection with Δ8-DR and 8-DR.R

Tissue	dpi	Log10/TCID50/g		P
		Δ8-DR	8-DR.R
Blood	2	<2.0	3.0 ± 0.1
	4	2.8 ± 0.3	6.7 ± 0.1	0.0002
	6	3.6 ± 0.4	7.4 ± 0.7	0.008
	8	4.8 ± 0.3	7.0 ± 0.0	0.006
Iliac lymph node	2	3.1 ± 0.5	6.3 ± 0.1	0.0004
	4	4.0 ± 1.0	5.4 ± 0.1
	6	6.7 ± 0.5	7.1 ± 0.2
	8	6.7 ± 0.3	6.8 ± 0.6
Spleen	2	<2.0	4.1 ± 0.2	0.0004
	4	4.9 ± 0.4	6.8 ± 0.2	0.015
	6	5.3 ± 0.3	6.9 ± 0.2	0.012
	8	5.7 ± 0.2	7.8 ± 0.3	0.005
Lung	2	<2.0	<2.0
	4	3.3 ± 0.8	5.8 ± 0.2	0.027
	6	5.6 ± 0.5	5.8 ± 0.2
	8	4.8 ± 0.4	6.1 ± 0.1
Liver	2	<2.0	2.3 ± 0.3
	4	4.0 ± 1.0	6.5 ± 0.6
	6	5.4 ± 0.3	6.1 ± 0.0
	8	5.3 ± 0.1	6.3 ± 0.3
Submandibular lymph node	2	<2.0	<2.0
	4	2.9 ± 0.5	5.0 ± 0.3	0.02
	6	5.6 ± 0.2	5.6 ± 0.2
	8	5.5 ± 0.0	7.5 ± 0.0	0.002
Bone marrow	2	<2.0	<2.0
	4	2.8 ± 0.8	5.2 ± 0.2	0.03
	6	3.2 ± 0.2	5.8 ± 0.4	0.018
	8	4.3 ± 0.3	5.9 ± 0.1	0.03