Table 4.
Analysis of selected SOD1 variants’ solvent accessibility and stability by NetSruf
Amino acid substitution | Class assignment | Relative surface accessibility (RSA) | Absolute surface accessibility (ASA) |
---|---|---|---|
G38R | Exposed | 0.497 | 39.118 |
G42D | Exposed | 0.327 | 25.72 |
G94R | Burried | 0.091 | 7.133 |
G94C | Burried | 0.091 | 7.133 |
I114T | Burried | 0.213 | 39.385 |
I152T | Burried | 0.226 | 41.752 |
G13R | Exposed | 0.375 | 29.548 |