Table 3.
Intercorrelation matrix between immune profiles and symptoms domain scores.
| Variables | Pure depression | Pure anxiety | Pure FF | Physiosomatic | Melancholia | GIS | Insomnia | Autonomic |
|---|---|---|---|---|---|---|---|---|
| Classical M1 | 0.417** | 0.393** | 0.229* | 0.295* | 0.398** | 0.283** | 0.347** | 0.147 |
| Alternative M2 | 0.332** | 0.297** | 0.171 | 0.230* | 0.306** | 0.188 | 0.269** | 0.112 |
| zM1–zM2 | 0.140 | 0.157 | 0.095 | 0.157 | 0.149 | 0.155 | 0.128 | 0.057 |
| Thelper (Th)-1 | 0.405** | 0.365** | 0.252* | 0.328** | 0.397** | 0.313** | 0.356** | 0.172 |
| Th-2 | 0.228* | 0.215* | 0.132 | 0.196 | 0.296** | 0.169 | 0.255* | 0.187 |
| zTh-1–zTh-2 | 0.332** | 0.282** | 0.224* | 0.249* | 0.189 | 0.270** | 0.190 | 0.029 |
| Th-17 | 0.242* | 0.238* | 0.135 | 0.204* | 0.267** | 0.213* | 0.242* | 0.181 |
| IRS | 0.424** | 0.406** | 0.263* | 0.331** | 0.410** | 0.338** | 0.389** | 0.157 |
| CIRS | 0.364** | 0.349** | 0.240* | 0.300** | 0.360** | 0.261* | 0.368** | 0.129 |
| zIRS–zCIRS | 0.142 | 0.137 | 0.053 | 0.074 | 0.120 | 0.056 | 0.049 | 0.067 |
| Immu-NT | 0.375** | 0.360** | 0.235* | 0.300** | 0.367** | 0.312** | 0.368** | 0.151 |
*p < 0.05, **p < 0.001.
IRS immune-inflammatory response system, CIRS compensatory immunoregulatory system, Immu-NT immune-associated neurotoxicity.
FF Fibro-Fatigue, GIS gastro-intestinal symptoms.