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. 2024 Mar 28;14:7344. doi: 10.1038/s41598-024-57350-1

Table 3.

Intercorrelation matrix between immune profiles and symptoms domain scores.

Variables Pure depression Pure anxiety Pure FF Physiosomatic Melancholia GIS Insomnia Autonomic
Classical M1 0.417** 0.393** 0.229* 0.295* 0.398** 0.283** 0.347** 0.147
Alternative M2 0.332** 0.297** 0.171 0.230* 0.306** 0.188 0.269** 0.112
zM1–zM2 0.140 0.157 0.095 0.157 0.149 0.155 0.128 0.057
Thelper (Th)-1 0.405** 0.365** 0.252* 0.328** 0.397** 0.313** 0.356** 0.172
Th-2 0.228* 0.215* 0.132 0.196 0.296** 0.169 0.255* 0.187
zTh-1–zTh-2 0.332** 0.282** 0.224* 0.249* 0.189 0.270** 0.190 0.029
Th-17 0.242* 0.238* 0.135 0.204* 0.267** 0.213* 0.242* 0.181
IRS 0.424** 0.406** 0.263* 0.331** 0.410** 0.338** 0.389** 0.157
CIRS 0.364** 0.349** 0.240* 0.300** 0.360** 0.261* 0.368** 0.129
zIRS–zCIRS 0.142 0.137 0.053 0.074 0.120 0.056 0.049 0.067
Immu-NT 0.375** 0.360** 0.235* 0.300** 0.367** 0.312** 0.368** 0.151

*p < 0.05, **p < 0.001.

IRS immune-inflammatory response system, CIRS compensatory immunoregulatory system, Immu-NT immune-associated neurotoxicity.

FF Fibro-Fatigue, GIS gastro-intestinal symptoms.