Table 4.
Top 20 gene-based results (Magma) after correction of multiple testing
| phenotypea | Description | Gene | CHR | ZSTAT | P | FDR.adjust Pb |
|---|---|---|---|---|---|---|
| PureC_Total | potassium voltage-gated channel subfamily C member 1 | KCNC1 | 11 | 6.03 | 8.18E-10 | 1.49E-05 |
| CVD_Total | general transcription factor IIIC subunit 1 | GTF3C1 | 16 | 5.41 | 3.24E-08 | 5.90E-04 |
| EWR_Total | cation channel sperm associated auxiliary subunit delta | CATSPERD | 19 | 5.16 | 1.22E-07 | 2.22E-03 |
| EIS_Total | solute carrier family 2 member 12 | SLC2A12 | 6 | 5.16 | 1.25E-07 | 2.27E-03 |
| EIS_Total | radial spoke head component 1 | RSPH1 | 21 | 5.01 | 2.74E-07 | 2.49E-03 |
| CVB_Total | mitogen-activated protein kinase 10 | MAPK10 | 4 | 5.09 | 1.76E-07 | 3.20E-03 |
| MS_Total | regulatory factor X8 | RFX8 | 2 | 4.96 | 3.57E-07 | 3.25E-03 |
| MS_Total | small lysine rich protein 1 | SMKR1 | 7 | 5.05 | 2.24E-07 | 3.25E-03 |
| CVK_Total | general transcription factor IIIC subunit 1 | GTF3C1 | 16 | 5.09 | 1.81E-07 | 3.30E-03 |
| EVB_Total | cation channel sperm associated auxiliary subunit delta | CATSPERD | 19 | 5.03 | 2.42E-07 | 4.40E-03 |
| CVB_Total | BCL2 interacting protein like | BNIPL | 1 | 4.86 | 5.87E-07 | 5.34E-03 |
| EVB_Total | cilia and flagella associated protein 65 | CFAP65 | 2 | 4.84 | 6.46E-07 | 5.89E-03 |
| BDS_Total | transmembrane serine protease 13 | TMPRSS13 | 11 | 4.96 | 3.48E-07 | 6.33E-03 |
| EVK_Total | cilia and flagella associated protein 65 | CFAP65 | 2 | 4.83 | 6.95E-07 | 1.27E-02 |
| EWR_Total | caveolae associated protein 2 | CAVIN2 | 2 | 4.46 | 4.19E-06 | 1.39E-02 |
| EWR_Total | Morf4 family associated protein 1 like 1 | MRFAP1L1 | 4 | 4.49 | 3.57E-06 | 1.39E-02 |
| EWR_Total | biogenesis of lysosomal organelles complex 1 subunit 4 | BLOC1S4 | 4 | 4.44 | 4.57E-06 | 1.39E-02 |
| EWR_Total | proline rich 22 | PRR22 | 19 | 4.54 | 2.81E-06 | 1.39E-02 |
| EWR_Total | dihydrouridine synthase 3 like | DUS3L | 19 | 4.57 | 2.43E-06 | 1.39E-02 |
| EDRAN_Mean | ankyrin repeat domain 50 | ANKRD50 | 4 | 4.80 | 7.76E-07 | 1.41E-02 |
aPlease refer to Table 10 for abbreviations of the phenotype.
bFDR-adjust P: Calculated by the R.program p.adjust using Benjamini-Hochberg procedure (BH).