Table 6.
Significant Pathway enrichment results (GAUSS) after correction of multiple testing (FDR < 0.05)
| GeneSet | Pvalue | Phenotype | FDR adjust Pa |
|---|---|---|---|
| REACTOME_RNA_POL_III_TRANSCRIPTION | 3.36E-08 | WO_Total | 1.60E-04 |
| BIOCARTA_P35ALZHEIMERS_PATHWAY | 3.41E-07 | EWR_Total | 1.62E-03 |
| REACTOME_P2Y_RECEPTORS | 3.94E-07 | CVK_Total | 1.88E-03 |
| REACTOME_KINESINS | 7.07E-07 | BDS_Total | 3.37E-03 |
| STOSSI_RESPONSE_TO_ESTRADIOL | 3.04E-06 | RC_MC | 1.45E-02 |
| IGLESIAS_E2F_TARGETS_DN | 4.29E-06 | CWR_Norm | 2.04E-02 |
| REACTOME_P2Y_RECEPTORS | 5.25E-06 | CVD_Total | 2.50E-02 |
| PID_S1P_META_PATHWAY | 9.02E-06 | CDICT_Total | 3.88E-02 |
| GOLUB_ALL_VS_AML_DN | 1.63E-05 | CDICT_Total | 3.88E-02 |
| BIOCARTA_AKAPCENTROSOME_PATHWAY | 2.00E-05 | CCR_Total | 4.76E-02 |
| BANDRES_RESPONSE_TO_CARMUSTIN_MGMT_48HR_UP | 2.00E-05 | CCR_Total | 4.76E-02 |
| LIM_MAMMARY_LUMINAL_PROGENITOR_UP | 2.00E-05 | EWR_Total | 4.76E-02 |
Please refer to Table 10 for abbreviations of the phenotypes. Full descriptions of each gene-set can be found by looking up the pathway names at https://www.gsea-msigdb.org/gsea/msigdb/.
aFDR-adjust P: Calculated by the R.program p.adjust using Benjamini-Hochberg procedure (BH).