Table 4.
Multivariate analysis of variables associated with eGFR decline (eGFR-CysC < 90 mL/min/1.73 m2) in healthy subjects.
| Variables | Per 1 increase | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|---|
| OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | ||
| Age | 1 year | 1.07 (1.03–1.10) | < 0.0001 | 1.08 (1.05–1.11) | < 0.0001 | 1.08 (1.05–1.11) | < 0.0001 |
| Uric acid | 1 mg/dL | 0.79 (0.61–1.03) | 0.08 | – | – | – | – |
| HbA1c | 1% | 2.93 (0.85–10.09) | 0.09 | – | – | – | – |
| Non-HDL-C | 1 mg/dL | 1.00 (0.93–1.01) | 0.57 | – | – | – | – |
| UACR | log 1SD = 0.28 | 1.43 (1.09–1.89) | 0.011 | 1.57 (1.17–2.11) | 0.003 | 1.49 (1.12–1.99) | 0.006 |
| TNFR1 | log 1SD = 0.09 | – | – | 2.51 (1.76–3.59) | < 0.0001 | – | – |
| TNFR2 | log1 SD = 0.09 | – | – | – | – | 1.88 (1.38–2.57) | < 0.0001 |
Model 1: age, uric acid, HbA1c, non-HDL-C, and UACR.
Model 2: age, UACR, and TNFR1.
Model 3: age, UACR, and TNFR2.
Abbreviations used in this table are the same as in Table 1.
CI confidence interval, OR odds ratio.