Table 2.
Maternal leukocyte counts | Maternal neutrophil counts | Maternal monocyte counts | ||||
---|---|---|---|---|---|---|
Q1 (under cut-off value) | Q2 (over cut-off value) | Q1 (under cut-off value) | Q2 (over cut-off value) | Q1 (under cut-off value) | Q2 (over cut-off value) | |
Mild HDP | < 9000 | 9000–< | < 6469.5 | 6469.5–< | < 336.3 | 336.3–< |
All participants, n | 27,060 | 11,134 | 24,769 | 13,425 | 14,524 | 23,670 |
Maternal leukocyte/neutrophil/monocyte counts, means ± SD | 7084 ± 1263 | 10,317 ± 1221 | 5009.6 ± 1024.9 | 7723.2 ± 1117.8 | 275.0 ± 44.6 | 447.5 ± 93.1 |
Cases, n | 529 | 329 | 480 | 378 | 251 | 607 |
Gestational age at time of blood collection, means ± SD | 11.2 ± 2.17 | 11.3 ± 2.18 | 11.2 ± 2.16 | 11.3 ± 2.18 | 11.2 ± 2.16 | 11.2 ± 2.18 |
Crude odds ratio (95% CI) | 1.0 (Reference) | 1.53 (1.33–1.76)* | 1.0 (Reference) | 1.47 (1.28–1.68)* | 1.0 (Reference) | 1.50 (1.29–1.74)* |
Severe HDP | < 9600 | 9600–< | < 5413.1 | 5413.1–< | < 376.3 | 376.3–< |
All participants, n | 30,577 | 7617 | 14,752 | 23,442 | 20,204 | 17,990 |
Maternal leukocyte/neutrophil/monocyte counts, means ± SD | 7332 ± 1374 | 10,817 ± 1174 | 4385.6 ± 859.5 | 6956.3 ± 1242.1 | 297.8 ± 52.9 | 476.4 ± 88.8 |
Cases, n | 261 | 109 | 105 | 265 | 154 | 216 |
Gestational age at time of blood collection, means ± SD | 11.2 ± 2.17 | 11.3 ± 2.18 | 11.1 ± 2.15 | 11.3 ± 2.18 | 11.2 ± 2.16 | 11.2 ± 2.18 |
Crude odds ratio (95% CI) | 1.0 (Reference) | 1.69 (1.35–2.11)* | 1.0 (Reference) | 1.59 (1.27–2.00)* | 1.0 (Reference) | 1.58 (1.29–1.95)* |
BMI body mass index, CI confidence intervals, HDP hypertensive disorders of pregnancy, SD standard deviation.
*P < 0.05 for logistic regression analysis.