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. 2024 Mar 27;14:7248. doi: 10.1038/s41598-024-55623-3

Table 2.

Odds ratios (95% CI) for mild/severe HDP according to cut-off value among 38,194 pregnancies.

Maternal leukocyte counts Maternal neutrophil counts Maternal monocyte counts
Q1 (under cut-off value) Q2 (over cut-off value) Q1 (under cut-off value) Q2 (over cut-off value) Q1 (under cut-off value) Q2 (over cut-off value)
Mild HDP  < 9000 9000–<   < 6469.5 6469.5–<   < 336.3 336.3–< 
 All participants, n 27,060 11,134 24,769 13,425 14,524 23,670
 Maternal leukocyte/neutrophil/monocyte counts, means ± SD 7084 ± 1263 10,317 ± 1221 5009.6 ± 1024.9 7723.2 ± 1117.8 275.0 ± 44.6 447.5 ± 93.1
 Cases, n 529 329 480 378 251 607
 Gestational age at time of blood collection, means ± SD 11.2 ± 2.17 11.3 ± 2.18 11.2 ± 2.16 11.3 ± 2.18 11.2 ± 2.16 11.2 ± 2.18
 Crude odds ratio (95% CI) 1.0 (Reference) 1.53 (1.33–1.76)* 1.0 (Reference) 1.47 (1.28–1.68)* 1.0 (Reference) 1.50 (1.29–1.74)*
Severe HDP  < 9600 9600–<   < 5413.1 5413.1–<   < 376.3 376.3–< 
 All participants, n 30,577 7617 14,752 23,442 20,204 17,990
 Maternal leukocyte/neutrophil/monocyte counts, means ± SD 7332 ± 1374 10,817 ± 1174 4385.6 ± 859.5 6956.3 ± 1242.1 297.8 ± 52.9 476.4 ± 88.8
 Cases, n 261 109 105 265 154 216
 Gestational age at time of blood collection, means ± SD 11.2 ± 2.17 11.3 ± 2.18 11.1 ± 2.15 11.3 ± 2.18 11.2 ± 2.16 11.2 ± 2.18
 Crude odds ratio (95% CI) 1.0 (Reference) 1.69 (1.35–2.11)* 1.0 (Reference) 1.59 (1.27–2.00)* 1.0 (Reference) 1.58 (1.29–1.95)*

BMI body mass index, CI confidence intervals, HDP hypertensive disorders of pregnancy, SD standard deviation.

*P < 0.05 for logistic regression analysis.