Table 1.
Oncotype DX ER Gene Scores and Recurrence Scores (RS) for early-stage ER-positive breast cancer, categorized by percentage of tumor cells with ER expression and intensity score (IS). *One case had two tumors in one block; one tumor was ER low and the other ER high, likely resulting in a positive quantitative ER gene score.
| ER Group | ER-Low subgroup | n | ER Gene score negative (%) | RS (range) | RS > 25 (%) |
|---|---|---|---|---|---|
| ER-low | Low weak | 12 | 11 (91.7)* | 27–70 | 12 (100) |
| Low only | 2 | 2 (100) | 42–56 | 2 (100) | |
| Weak only | 13 | 10 (76.9) | 25–65 | 11 (84.6) | |
| ER-high | 46 | 0 (0) | 0–43 | 6 (12.0) |