Table 3. PPVs for the four score groups according to clinical and radiological factors.
| Variable | Group 1 (10–49) | Group 2 (50–69) | Group 3 (70–89) | Group 4 (90–99) | Overall | P * | |
|---|---|---|---|---|---|---|---|
| Overall | 9.3 (38/409) | 33.8 (25/74) | 66.0 (33/50) | 95.1 (117/123) | 32.5 (213/656) | < 0.001 | |
| Indication | |||||||
| Screening | 5.1 (12/235) | 29.0 (9/31) | 57.9 (11/19) | 96.3 (26/27) | 18.6 (58/312) | < 0.001 | |
| Diagnostic | 14.9 (26/174) | 37.2 (16/43) | 71.0 (22/31) | 94.8 (91/96) | 45.1 (155/344) | < 0.001 | |
| P † | 0.001 | 0.457 | 0.349 | 0.725 | < 0.001 | ||
| Palpability | |||||||
| Yes | 16.0 (20/125) | 47.1 (16/34) | 69.7 (23/33) | 94.7 (90/95) | 51.9 (149/287) | < 0.001 | |
| No | 6.3 (18/284) | 22.5 (9/40) | 58.8 (10/17) | 96.4 (27/28) | 17.3 (64/369) | < 0.001 | |
| P † | 0.007 | 0.023 | 0.449 | 0.686 | < 0.001 | ||
| Density | |||||||
| Category A | 16.7 (1/6) | 75.0 (3/4) | 100.0 (2/2) | 100.0 (4/4) | 62.5 (10/16) | 0.038 | |
| Category B | 20.0 (7/35) | 66.7 (4/6) | 77.8 (7/9) | 100.0 (32/32) | 61.0 (50/82) | < 0.001 | |
| Category C | 7.3 (16/218) | 27.5 (11/40) | 58.6 (17/29) | 90.0 (54/60) | 28.2 (98/347) | < 0.001 | |
| Category D | 9.3 (14/150) | 29.2 (7/24) | 70.0 (7/10) | 100.0 (27/27) | 26.1 (55/211) | < 0.001 | |
| P † | 0.105 | 0.076 | 0.501 | 0.085 | < 0.001 | ||
| Finding | |||||||
| Asymmetry | 13.9 (11/79) | 31.6 (6/19) | 28.6 (2/7) | 80.0 (8/10) | 23.5 (27/115) | < 0.001 | |
| Distortion | 40.0 (2/5) | 75.0 (3/4) | 100.0 (2/2) | 100.0 (2/2) | 69.2 (9/13) | 0.279 | |
| Mass | 22.4 (11/49) | 64.7 (11/17) | 77.8 (21/27) | 96.2 (50/52) | 64.1 (93/145) | < 0.001 | |
| Mass with microcalcifications | 35.7 (5/14) | 40.0 (2/5) | 75.0 (3/4) | 97.7 (42/43) | 78.8 (52/66) | < 0.001 | |
| Microcalcifications only | 8.1 (9/111) | 13.6 (3/22) | 50.0 (5/10) | 93.8 (15/16) | 20.1 (32/159) | < 0.001 | |
| Negative | 0.0 (0/151) | 0.0 (0/7) | NA (0/0) | NA (0/0) | 0.0 (0/158) | NA | |
| P † | 0.008 | 0.009 | 0.079 | 0.213 | < 0.001 | ||
Data are presented as a percentage of the number of breasts.
*P-value calculated for the difference in PPV among score groups, †P-value calculated for difference in PPV between/among column categories in each variable (e.g., screening vs. diagnostic).
PPV = positive predictive value, NA = not applicable