Table 1. Summary of patient presentation.

* Approximate number of days qualifying as migraine days based on ICHD-3 criteria. ** Approximate year of prior diagnosis of chronic migraine.

Patient	Age		Race/ethnicity	Headache days per month	Migraine days per month*	Migraine headache characteristics	Aura	Prior treatments	Initial diagnosis**
Patient 1	24	Caucasian		Daily	8-12	Headaches lasting >4 hours, unilateral location, moderate-severe pulsatile pain, associated nausea, and photophobia, triggered by exercise	Yes	Nortriptyline	2020
Patient 2	25	Caucasian		Unavailable	8-12	Headaches lasting >4 hours, unilateral location, moderate-severe pulsatile pain, associated nausea, and photophobia, triggered by exercise	Yes	Caffeine, diphenhydramine	2018
Patient 3	25	Hispanic		Daily	8-12	Headaches lasting >4 hours, unilateral location, moderate-severe pulsatile pain, associated nausea, and photophobia	Yes	Nerve block, botox injection, acupuncture, physical therapy, fremanezumab, unknown oral medications	2015