Table 3.
Associations of multiple sclerosis, ulcerative colitis, Kawasaki disease with COVID-19 vaccination in MR analyses.
| Outcome | SNP (n) | Method | OR | p_value | 95%(CI) |
|---|---|---|---|---|---|
| MS | 51 | MR Egger | 4.08 | 0.01 | 1.59–10.52 |
| MS | 51 | Weighted median | 1.75 | 0.02 | 1.08–2.83 |
| MS | 51 | Inverse variance weighted | 1.53 | 0.02 | 1.06–2.20 |
| MS | 51 | Simple mode | 2.22 | 0.16 | 0.75–6.54 |
| MS | 51 | Weighted mode | 2.09 | 0.18 | 0.73–5.98 |
| UC | 28 | MR Egger | 1.00 | 0.52 | 0.99–1.01 |
| UC | 28 | Weighted median | 1.00 | 0.30 | 1.00–1.00 |
| UC | 28 | Inverse variance weighted | 1.00 | 0.04 | 1.00–1.00 |
| UC | 28 | Simple mode | 1.00 | 0.47 | 1.00–1.01 |
| UC | 28 | Weighted mode | 1.00 | 0.50 | 1.00–1.00 |
| Kawasaki disease | 1 | Wald ratio | 5982.14 | 0.04 | 1.43–25033402.50 |
MS, multiple sclerosis; UC, ulcerative colitis; CI, confidence interval; IVW, inverse-variance weighted; OR, odds ratio.