Table 2.
Differences in diabetes distress and depressive symptoms at 1 year from baseline
| Glargine vs. other three groups combined | Liraglutide vs. glargine group | Liraglutide vs. glimepiride and sitagliptin groups combined | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Difference* | LL | UL | P value | Difference* | LL | UL | P value | Difference* | LL | UL | P value | |
| Diabetes distress | ||||||||||||
| Primary diabetes distress | −0.101 | −0.164 | −0.037 | 0.002 | 0.042 | −0.037 | 0.119 | 0.289 | −0.097 | −0.169 | −0.026 | 0.008 |
| Emotional distress subscale | −0.065 | −0.130 | −0.000 | 0.049 | 0.023 | −0.057 | 0.103 | 0.572 | −0.073 | −0.148 | 0.003 | 0.058 |
| Regimen-related distress subscale | −0.135 | −0.213 | −0.058 | 0.001 | 0.061 | −0.033 | 0.155 | 0.206 | −0.122 | −0.208 | −0.036 | 0.006 |
| Physician-related distress subscale | −0.061 | −0.129 | 0.006 | 0.075 | 0.027 | −0.053 | 0.106 | 0.511 | −0.056 | −0.130 | 0.017 | 0.133 |
| Interpersonal distress subscale | −0.067 | −0.143 | 0.010 | 0.088 | −0.035 | −0.123 | 0.053 | 0.438 | −0.165 | −0.247 | −0.083 | <0.001 |
| Depressive symptoms | ||||||||||||
| Primary depressive symptoms | −0.165 | −0.487 | 0.158 | 0.316 | 0.307 | −0.095 | 0.709 | 0.135 | 0.189 | −0.135 | 0.513 | 0.252 |
| Somatic symptoms score | −0.025 | −0.070 | 0.020 | 0.275 | 0.056 | −0.001 | 0.112 | 0.053 | 0.043 | −0.004 | 0.089 | 0.072 |
| Cognitive-affective symptoms score | −0.013 | −0.059 | 0.033 | 0.574 | 0.010 | −0.046 | 0.065 | 0.737 | −0.008 | −0.052 | 0.036 | 0.724 |
LL, lower limit; UL, upper limit. Significant P values are in boldface.
*Difference in means at 1 year.