Table 1.
Underlying causes of death by treatment group (total deaths = 153)
All causes | Cardiovascular* | Cancer | Other† | |||||
---|---|---|---|---|---|---|---|---|
N | % (CI) | N | % (CI) | N | % (CI) | N | % (CI) | |
Glimepiride | 43 | 28.1 (21.6, 35.7) | 13 | 30.2 (18.6, 45.1) | 13 | 30.2 (18.6, 45.1) | 17 | 39.5 (26.4, 54.4) |
Glargine | 42 | 27.5 (21.0, 35.0) | 19 | 45.2 (31.2, 60.1) | 12 | 28.6 (17.2, 43.6) | 11 | 26.2 (15.3, 41.1) |
Sitagliptin | 41 | 26.8 (20.4, 34.3) | 19 | 46.3 (32.1, 61.3) | 9 | 22.0 (12.0, 36.7) | 13 | 31.7 (19.6, 47.0) |
Liraglutide | 27 | 17.6 (12.4, 24.5) | 8 | 29.6 (15.9, 48.5) | 7 | 25.9 (13.2, 44.7) | 12 | 44.4 (27.6, 62.7) |
The percentages (95% CI) in the “all causes” column refer to the proportion of fatal cases in each treatment group. For the remaining columns, the percentages (95% CI) refer to the proportion of cause-specific mortality by randomized treatment.
*Cardiovascular: “cardiovascular-cause” mortality, including death from MACE (known MI or stroke or within 30 days of an MI or stroke), presumed CVD (sudden death with a history of CVD and absence of other cause), sudden death without a specific noncardiac cause, and unknown cause of death.
†Other includes other, infection, chronic liver disease, respiratory, pneumonia, accident, suicide, end-stage renal (end-stage renal death), overdose, and dementia.