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. 2024 Jan 22;47(4):589–593. doi: 10.2337/dc23-1356

Table 1.

Underlying causes of death by treatment group (total deaths = 153)

All causes Cardiovascular* Cancer Other†
N % (CI) N % (CI) N % (CI) N % (CI)
Glimepiride 43 28.1 (21.6, 35.7) 13 30.2 (18.6, 45.1) 13 30.2 (18.6, 45.1) 17 39.5 (26.4, 54.4)
Glargine 42 27.5 (21.0, 35.0) 19 45.2 (31.2, 60.1) 12 28.6 (17.2, 43.6) 11 26.2 (15.3, 41.1)
Sitagliptin 41 26.8 (20.4, 34.3) 19 46.3 (32.1, 61.3) 9 22.0 (12.0, 36.7) 13 31.7 (19.6, 47.0)
Liraglutide 27 17.6 (12.4, 24.5) 8 29.6 (15.9, 48.5) 7 25.9 (13.2, 44.7) 12 44.4 (27.6, 62.7)

The percentages (95% CI) in the “all causes” column refer to the proportion of fatal cases in each treatment group. For the remaining columns, the percentages (95% CI) refer to the proportion of cause-specific mortality by randomized treatment.

*Cardiovascular: “cardiovascular-cause” mortality, including death from MACE (known MI or stroke or within 30 days of an MI or stroke), presumed CVD (sudden death with a history of CVD and absence of other cause), sudden death without a specific noncardiac cause, and unknown cause of death.

†Other includes other, infection, chronic liver disease, respiratory, pneumonia, accident, suicide, end-stage renal (end-stage renal death), overdose, and dementia.