TABLE 3.
Levels of replication of parental and chimeric PIVs in the upper and lower respiratory tracts of hamstersa
| Virus | Virus titer (mean log10 TCID50/g ± SE) in:
|
|||
|---|---|---|---|---|
| Nasal turbinates
|
Lungs
|
|||
| Day 4 | Day 5 | Day 4 | Day 5 | |
| PIV1/Wash64 | 5.2 ± 0.24 | 5.2 ± 0.12 | 5.0 ± 0.31 | 5.0 ± 0.38 |
| rPIV3-1 | 4.9 ± 0.23 | 6.2 ± 0.17 | 5.8 ± 0.15 | 6.0 ± 0.09 |
| rPIV3/JS | 4.5 ± 0.09 | 5.0 ± 0.18 | 5.1 ± 0.26 | 5.0 ± 0.32 |
a
Each hamster was infected intranasally with 105.0 TCID50 of the indicated virus, and lungs and nasal turbinates were removed on day 4 or 5 after infection. The titers are means for six animals per day.