Table 4.
Cognitive function.
| Variable | Treatment | Day 0 | Day 7 | Treatment | ||
|---|---|---|---|---|---|---|
| Mean SD | Mean SD | Mean SE | p-Value | |||
| Word (counts) |
PL | 109.3 ± 17.7 | 111.0 ± 13.4 | 110.1 ± 3.14 | Time | 0.006 |
| CN | 113.2 ± 12.7 | 116.0 ± 14.2 | 114.8 ± 2.72 | Trt | 0.15 | |
| CAF | 116.1 ± 14.5 | 119.5 ± 17.3 | 117.7 ± 3.21 | T×T | 0.55 | |
| CO | 118.1 ± 20.3 | 119.7 ± 16.4 | 118.9 ± 3.69 | |||
| Color (counts) |
PL | 83.6 ± 16.2 | 86.41 ± 15.1 | 85.0 ± 3.14 | Time | 0.003 |
| CN | 83.4 ± 13.4 | 87.0 ± 13.8 * | 85.2 ± 2.74 | Trt | 0.26 | |
| CAF | 92.1 ± 15.5 | 92.5 ± 16.6 | 92.3 ± 3.21 | T×T | 0.64 | |
| CO | 90.6 ± 17.3 | 91.4 ± 17.2 | 91.0 ± 3.45 | |||
| Word–Color (counts) |
PL | 51.3 ± 18.2 | 59.8 ± 14.3 b,* | 55.5 ± 3.39 | Time | 0.01 |
| CN | 54.0 ± 11.2 | 56.8 ± 10.8 | 55.4 ± 2.22 | Trt | 0.03 | |
| CAF | 62.5 ± 14.8 | 62.7 ± 14.8 a,c | 62.6 ± 2.95 | T×T | 0.04 † | |
| CO | 58.5 ± 18.2 | 65.9 ± 17.3 b,* | 62.2 ± 3.63 | |||
| Total Stroop Results (counts) |
PL | 244.3 ± 48.1 | 257.2 ± 40.6 * | 250.7 ± 8.98 | Time | 0.003 |
| CN | 250.6 ± 35.5 | 260.3 ± 35.1 | 255.5 ± 7.12 | Trt | 0.03 | |
| CAF | 270.6 ± 38.7 | 274.8 ± 46.2 | 272.7 ± 8.52 | T×T | 0.67 | |
| CO | 267.2 ± 53.8 | 277.1 ± 46.9 | 273.1 ± 10.2 | |||
Values are means ± standard deviations. Multivariate analysis revealed overall Wilks’ Lambda time (p = 0.71), treatment (p = 0.34), and time × treatment (p = 0.97). p-values for the Greenhouse–Geisser time and the time-by-treatment (T×T) interaction are presented alongside univariate group p-values. † indicates a significant between-treatment difference, * represents p < 0.05 difference from baseline. a denotes a significant difference from PL. b denotes a significant difference from CAF. c denotes a significant difference from CO. Trt = treatment, T×T = time × treatment interaction.