Table 7.
Variable | Treatment | Day 0 | Day 7 | ||
---|---|---|---|---|---|
Mean SD | Mean SD | p-Value | |||
WBC Count (×103/μL) | PL | 6.20 ± 1.71 | 6.15 ± 1.51 | Time | 0.35 |
CN | 5.96 ± 1.39 | 6.46 ± 1.83 | Trt | 0.30 | |
CAF | 6.29 ± 1.45 | 6.11 ± 1.74 | T×T | 0.89 | |
CO | 6.45 ± 1.45 | 6.33 ± 1.61 | |||
RBC Count (×106/μL) | PL | 4.99 ± 0.92 | 5.19 ± 0.21 | Time | 0.92 |
CN | 5.25 ± 0.26 | 5.22 ± 0.21 | Trt | 0.45 | |
CAF | 5.19 ± 0.27 | 5.14 ± 0.18 | T×T | 0.41 | |
CO | 5.22 ± 0.23 | 5.13 ± 0.24 | |||
Hemoglobin (g/dL) | PL | 16.2 ± 1.73 | 15.7 ± 0.41 | Time | 0.09 |
CN | 15.9 ± 0.74 | 15.9 ± 0.71 | Trt | 0.33 | |
CAF | 15.9 ± 0.67 | 15.7 ± 0.73 | T×T | 0.78 | |
CO | 15.7 ± 0.65 | 15.6 ± 0.61 | |||
Hematocrit (%) | PL | 49.1 ± 4.72 | 47.9 ± 1.61 | Time | 0.04 |
CN | 48.3 ± 1.91 | 48.4 ± 2.11 | Trt | 0.42 | |
CAF | 48.1 ± 1.79 | 47.4 ± 1.96 | T×T | 0.92 | |
CO | 48.0 ± 1.61 | 47.5 ± 1.84 | |||
MCV (fL) | PL | 92.7 ± 3.98 | 92.6 ± 3.85 b | Time | 0.34 |
CN | 92.3 ± 3.91 | 92.7 ± 3.80 a,c | Trt | 0.07 | |
CAF | 92.7 ± 3.87 | 92.3 ± 3.59 b,d | T×T | 0.64 | |
CO | 92.2 ± 3.68 | 92.6 ± 3.55 c | |||
MCH (pg/cell) | PL | 30.7 ± 1.61 | 30.3 ± 1.53 b,d | Time | 0.61 |
CN | 30.4 ± 1.37 | 30.5 ± 1.41 a | Trt | 0.01 | |
CAF | 30.7 ± 1.57 | 30.6 ± 1.48 | T×T | 0.60 | |
CO | 30.3 ± 1.51 | 30.6 ± 1.42 a | |||
MCHC (g/dL) | PL | 33.1 ± 0.57 | 32.7 ± 0.61 | Time | 0.28 |
CN | 32.9 ± 0.48 | 32.9 ± 0.50 | Trt | 0.34 | |
CAF | 33.1 ± 0.71 | 33.1 ± 0.62 | T×T | 0.39 | |
CO | 32.9 ± 0.58 | 33.0 ± 0.51 | |||
RDW (%) | PL | 12.8 ± 0.69 | 12.6 ± 0.66 | Time | 0.77 |
CN | 12.7 ± 0.47 | 12.6 ± 0.68 | Trt | 0.64 | |
CAF | 12.7 ± 0.81 | 12.6 ± 0.95 | T×T | 0.91 | |
CO | 12.7 ± 0.51 | 12.7 ± 0.64 | |||
Platelet Count (×103/μL) | PL | 241.7 ± 55.5 | 234.1 ± 46.5 | Time | 0.33 |
CN | 262.3 ± 43.3 | 257.6 ± 42.8 | Trt | 0.002 | |
CAF | 252.5 ± 45.5 | 244.1 ± 41.4 | T×T | 0.47 | |
CO | 261.9 ± 38.6 | 254.1 ± 40.9 |
Values are means ± standard deviations. All variables were analyzed by MANOVA. MANOVA analysis revealed overall Wilks’ Lambda time (p = 0.43), treatment (p = 0.92), and time × treatment (p = 0.97). p-values for the Greenhouse–Geisser time and the time-by-treatment (T×T) interaction are presented alongside univariate group p-values. a denotes a significant difference from PL. b denotes a significant difference from CN. c denotes a significant difference from CAF. d denotes a significant difference from CO. Trt = treatment, T×T = time × treatment interaction.