Table 1.
Basic characteristics of patient groups.
| Patient Type | Rare Bone Disease Group (N = 50) | Osteoporosis Group (N = 51) |
Control Group (N = 52) |
||||
|---|---|---|---|---|---|---|---|
| OI (N = 17) | HPP (N = 17) | XLH (N = 16) | Total | p-Value * | |||
| Age, mean (SD) | 47.6 (±15.6) | 55.9 (±13.9) | 42.5 (±16.0) | 48.8 (±15.9) | 66.6 (±10.0) | 50.8 (±16.3) | <0.001 |
| Gender, male, N (%) | 5 (29.4) | 7 (41.2) | 1 (6.3) | 13 (26.0) | 5 (9.8) | 14 (26.9) | 0.06 |
| Family status, N (%) | 0.09 | ||||||
| Single | 4 (23.5) | 1 (5.9) | 3 (18.8) | 8 (16.0) | 4 (7.8) | 13 (25.0) | |
| Married or cohabiting | 9 (52.9) | 10 (58.8) | 9 (56.3) | 28 (56.0) | 25 (49.0) | 30 (57.7) | |
| Divorced | 2 (11.8) | 3 (17.6) | 4 (25.0) | 9 (18) | 13 (25.5) | 5 (9.6) | |
| Widowed | 0 (0.0) | 1 (5.9) | 0 (0.0) | 1 (2.0) | 5 (9.8) | 4 (7.7) | |
| Educational level, N (%) | 0.07 | ||||||
| Basic | 9 (52.9) | 7 (41.2) | 10 (62.5) | 26 (52.0) | 19 (37.3) | 28 (53.8) | |
| Secondary | 3 (17.6) | 2 (11.8) | 0 (0.0) | 5 (10.0) | 16 (31.4) | 8 (15.4) | |
| Tertiary | 3 (17.6) | 6 (35.3) | 6 (37.5) | 15 (30.0) | 13 (25.5) | 16 (30.8) | |
| Employment status, employed, N (%) | 9 (52.9) | 8 (47.1) | 12 (75.0) | 29 (58.0) | 22 (43.1) | 41 (78.8) | <0.001 |
| BMI | 25.4 (±6.2) | 27.2 (±5.1) | 25.8 (±5.7) | 26.2 (±5.6) | 24.2(±3.9) | 26.4 (±4.7) | 0.16 |
RBD, rare bone disease; OI, osteogenesis imperfecta; HPP, hypophosphatasia; XLH, x-linked hypophosphatemia; BMI, body mass index; * p-value for group differences among RBD, OPO and CON groups. Statistically significant p-values are marked in bold. Missing values: Family status: RBD, 4 (8%); OPO, 4 (7.8%); CON, 0 (0%). Educational level: RBD, 4 (8%); OPO, 3 (5.9%); CON, 0 (0%). Employment status: RBD, 4 (8.0%); OPO, 1 (2.0%); CON, 0 (0%). BMI: RBD, 4 (8%); OPO, 4 (7.8%); CON, 7 (13.5%). Data are expressed as percentages for categorical variables and means and ± standard deviations for continuous variables.