Table 2. Model Performance With and Without N-Terminal Pro–Brain Natriuretic Peptide (NT-proBNP) Level Assessed by Harrell C Statistic.

	C statistic (95% CI)			Difference in C statistic (95% CI)
	(1) NT-proBNP alone	(2) Baseline model without NT-proBNP	(3) Baseline model with NT-proBNP	(2) vs (1)	P value	(3) vs (1)	P value
HFH/CV death
1 y	0.66 (0.64 to 0.68)	0.70 (0.68 to 0.72)	0.73 (0.71 to 0.75)	0.04 (0.01 to 0.06)	.01	0.07 (0.05 to 0.09)	<.001
2 y	0.65 (0.63 to 0.66)	0.68 (0.66 to 0.70)	0.71 (0.69 to 0.73)	0.03 (0.01 to 0.05)	.009	0.06 (0.05 to 0.08)	<.001
CV death
1 y	0.69 (0.65 to 0.73)	0.72 (0.68 to 0.76)	0.75 (0.71 to 0.79)	0.03 (−0.02 to 0.08)	.24	0.06 (0.03 to 0.09)	<.001
2 y	0.65 (0.62 to 0.68)	0.69 (0.66 to 0.71)	0.71 (0.68 to 0.74)	0.04 (0 to 0.07)	.03	0.06 (0.04 to 0.08)	<.001
All-cause death
1 y	0.65 (0.62 to 0.68)	0.68 (0.65 to 0.71)	0.71 (0.68 to 0.74)	0.02 (−0.01 to 0.06)	.22	0.05 (0.03 to 0.07)	<.001
2 y	0.62 (0.60 to 0.64)	0.66 (0.64 to 0.68)	0.68 (0.66 to 0.70)	0.04 (0.02 to 0.06)	<.001	0.06 (0.04 to 0.07)	<.001

Abbreviations: CV, cardiovascular; HFH, heart failure hospitalization.