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. 2024 Mar 15;29(6):1309. doi: 10.3390/molecules29061309

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Impact of test compounds on the exudate content of TNF-α (A) PGE2 (B) in a carrageenan-induced paw edema inflammation model. The data are presented as mean ± SD and were analyzed using one-way ANOVA, followed by Tukey’s multiple comparisons test; n = 6. ^a Significantly different from the control group at p < 0.05, ^b Significantly different from the carrageenan group at p < 0.05, ^c Significantly different from the celecoxib group at p < 0.05, ^d Significantly different from the mefenamic acid group at p < 0.05. TNF-α: tumor necrosis factor-alpha; PGE2: prostaglandin E2; Con: control; Car: carrageenan; Cel: celecoxib; Mef: mefenamic acid.