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. 2024 Mar 20;29(6):1385. doi: 10.3390/molecules29061385

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(A) Isobologram analysis of the TCAM and ciprofloxacin combination when tested at multiple ratios against E. coli; (B) Isobologram of ratios of TCAW extract in combination with ciprofloxacin against K. pneumoniae. FIC values are displayed as the means of two independent repeats (n = 2). Ratio = % extract: % antibiotic. Values below the 0.5/0.5 line represent synergy; the segment between the 0.5/0.5 and 1/1 lines represents additive interactions. Only the synergistic and additive ratios are displayed in these graphs.