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. 2024 Mar 4;16(3):359. doi: 10.3390/pharmaceutics16030359

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Wound healing activity observed after 24 h incubation of human normal skin fibroblasts (Hs27 cells) with hydrogel base (2.5CS/2Gel), hydrogel-based scaffold (2.5CS/2Gel/10Ex), Scutellaria baicalensis extract (Extract), and baicalin (Bai). Samples of 2.5CS/2Gel and 2.5CS/2Gel/10Ex were mixed with the culture medium to obtain 1% solution (0.1 mL of 2.5CS/2Gel or 2.5CS/2Gel/10Ex + 9.9 mL of medium). Concentration of Extract was adjusted to its content in 2.5CS/2Gel/10Ex, while Bai was tested at its concentration determined in Scutellaria baicalensis extract. Results were statistically analyzed by a one-way ANOVA with a post hoc Tukey’s test. Statistical significance was designated as **** when p < 0.0001.