Table 3.
TTV viral load and TTV species in plasma samples from renal transplant patients (n = 27) using two PCR assays.
| n Patients | ID Samples | Time after Transplantation (month) | TTV Viral Load (Log10 copies/mL) |
n TTV Species | Anelloviruses | Viral Infection (Virus, Days after Transplantation) |
Graft Rejection (Days after Transplantation) |
||
|---|---|---|---|---|---|---|---|---|---|
| Home Brew PCR | R-GENE® PCR | TTV Species | Other Anelloviruses | ||||||
| 1 | M 1_50945 | Pre Tx | 5.4 | 5.0 | 6 | 3, 13, 15, 17, 18, 29 | - | NO | NO |
| 2 | M 2_48365 | Pre Tx | 4.3 | 3.9 | 8 | 1, 9 (11/12), 13, 17, 18, 19, 21, 24 | - | NO | NO |
| 3 | M 3_10226 | Pre Tx | 5.0 | 3.9 | 5 | 1, 3, 9 (11/12) *, 13, 24 (22/24) * | - | NO | NO |
| 4 | M 4_50378 | Pre Tx | 4.7 | 4.0 | 6 | 3, 9 (12), 13, 15 (16), 18, 24 | - | NO | NO |
| 5 | M 5_46007 | Pre Tx | 4.4 | 4.0 | 4 | 13, 15 (16), 18, 24 | - | NO | NO |
| 6 | M 6_53410 | Pre Tx | 4.2 | 2.9 | 4 | 3, 9 (12), 15 (16), 20 | - | YES (CMV, +163) | YES (+38) |
| 7 | M 7_48016 | Pre Tx | 5.6 | 4.9 | 8 | 1, 3, 5, 9 (11/12) *, 10, 13, 19, 24 | - | NO | NO |
| 8 | M 8_10348 | Pre Tx | 4.6 | 4.2 | 5 | 3, 13, 18, 24, 29 | - | YES (BKPyV, +101) | NO |
| 9 | M 9_49489 | Pre Tx | 4.3 | 4.1 | 10 | 3, 5, 13, 15 (16), 17, 18, 20, 21, 24 (22,24), 29 | - | NO | NO |
| 10 | M 10_51173 | 1 | 3.9 | 0.0 | 3 | 3, 9 (12), 13 | - | NO | NO |
| 11 | M 11_49748 | 1 | 4.6 | 2.3 | 7 | 1, 5, 9 (12), 13, 15 (16), 24 (22), 29 | - | NO | NO |
| 12 | M 12_53806 | 3 | 8.5 | 7.0 | 5 | 3, 5, 15, 18, 21 | - | YES (CMV, +105) | NO |
| 13 | M 13_49964 | 3 | 8.2 | 7.8 | 4 | 1, 3, 18, 21 | - | NO | YES (+220) |
| 14 | M 14_51577 | 3 | 8.2 | 7.7 | 7 | 3, 6, 9 (11), 18, 21, 24, 29 (28) | - | YES (BKPyV, +156) | YES (+36) |
| 15 | M 15_50343 | 3 | 8.5 | 7.7 | 2 | 15 (16), 29 (28/29) * | - | NO | NO |
| 16 | M 16_47955 | 3 | 8.5 | 6.7 | 2 | 3, 5 | - | NO | NO |
| 17 | M 17_ 46592 | 3 | 8.2 | 7.2 | 7 | 3, 5, 9 (11), 13, 18, 24 (22), 29 (28) | - | YES (CMV, +221) | NO |
| 18 | M 18_48748 | 6 | 3.7 | 6.1 | 2 | 3, 5 | TTMDV | NO | NO |
| 19 | M 19_49833 | 6 | 8.5 | 6.9 | 1 | 3 | - | NO | NO |
| 20 | M 20_49667 | 6 | 7.3 | 5.5 | 7 | 1, 3, 9, 18, 21, 24, 29 (27) | - | NO | NO |
| 21 | M 21_10232 | 6 | 8.4 | 7.6 | 2 | 3, 24 | - | NO | YES (+52) |
| 22 | M 22_10175 | 12 | 4.1 | 7.1 | 5 | 1, 5, 13, 18, 21 | TTMDV | NO | NO |
| 23 | M 23_11085 | 12 | 6.9 | 5.0 | 2 | 20, 24 (22) | - | NO | YES (+86) |
| 24 | M 24_10839 | 12 | 8.6 | 7.2 | 2 | 5, 24 | - | NO | NO |
| 25 | M 25_46868 | Pre Tx | 4.0 | 3.4 | 4 | 1, 3, 9 (12), 13 | - | NO | NO |
| M 26_51364 | 12 | 8.4 | 7.2 | 1 | 19 | - | |||
| 26 | M 27_51795 | Pre Tx | 3.6 | 4.3 | 5 | 1, 5, 15 (16), 18, 29 | - | NO | NO |
| M 28_10274 | 6 | 3.0 | 8.9 | 0 | TTMV | ||||
| 27 | M 29_46175 | Pre Tx | 6.4 | 5.5 | 2 | 3, 5 | - | YES (BKPyV, +307) | NO |
| M 30_49183 | 9 | 8.1 | 7.2 | 1 | 21 | - | |||
Pre Tx: pre-transplant sample. TTMV: Torque Teno Mini Virus; TTMDV: Torque Teno Midi Virus. (): TTV species assigned denomination in the previous taxonomical classification. (/) *: variants of TTV species named according to the previous taxonomical classification.