Figure 4.
Effect of the additions of increasing volumes of insulin fibrils/aggregates on the fluorescence emission spectra of compound 3: (A) at λex = 304 nm; (B) at λex = 327 nm, employing method A for protein aggregation. Same experiments for compound 4: (C) at λex = 304 nm; (D) at λex = 327 nm, employing method A for protein aggregation. The protein:sensor molar ratios are in the inset. The peaks at 340 (A,C) and 370 nm (B,D) correspond to Raman dispersion.