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Fluorescence quenching studies. Stern–Volmer (KSV) and binding constants (K) obtained for the fluorene derivatives and the reference compounds with fibrils of insulin β-amyloid protein. The correlation obtained (R2) was higher than 0.98 in all cases.
| Compound | K SV | K |
|---|---|---|
| Thioflavin T | 2.11 × 104 | 1.26 × 103 |
| GN8 | 1.63 × 104 | 1.01 × 104 |
| 4 | 1.09 × 105 | 1.46 × 105 |
