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. 2024 Feb 29;16(3):344. doi: 10.3390/pharmaceutics16030344

Scheme 1.

Scheme 1

Scheme of self-healing hydrogel synthesis based on crosslinking reaction of polyvinyl alcohol (PVA, red color) and carboxymethyl chitosan (CmChi, green color) with borax (purple color) and S-Nitrosoglutathione (GSNO, pink color) as nitric oxide donor. The borate ester and hydrogen bonds were obtained during the crosslinking reaction.