Table 2.
Positive effects of the ketogenic diet in the study groups.
| Positive Effects of the KD | No. of Patients in Whom Improvement Was Observed/No. of Patients with a Problem (%) | All n = 21 |
|
|---|---|---|---|
| Group 1 MD + KD n = 11 |
Group 3 KD without MD n = 10 |
||
| Seizure reduction (total) | 2/2 (100%) | 6/8 (75%) | 8/10 (80%) |
| 100% reduction in seizures | 1/2 (50%) | 1/8 (12.5%) | 2/10 (20%) |
| Reduction in seizures by >90% | 0 | 0 | 0 |
| Seizure reduction by 50–90% | 1/2 (50%) | 4/8 (50%) | 5/10 (50%) |
| <50% reduction in seizures | 0 | 1/8 (12.5%) | 1/10 (10%) |
| Reduction in the number of antiepileptic drugs administered | 2/5 (40%) | 0/8 | 2/13 (15.4%) |
| Improvement of muscle tone | 8/9 (88.8%) * | 1/7 (14.3%) | 9/16 (56.2%) |
| Reduction in extra movements (tremor, ataxia, dystonia) | 5/6 (83.3%) | 3/6 (50%) | 8/12 (66.7%) |
* Statistically significant difference p < 0.05 (the chi-square test of independence with Yates correction). KD—ketogenic diet, MD—mitochondrial disease, No—number.