Table 2. Objectifiable parameters for an evaluation of long-term mepolizumab therapy (> 12 months) (modified from [6]).

All symptoms are only moderately pronounced or at least improved compared to the status before the start of therapy

Total nasal polyp score < 4 (added on both sides)

Nasal congestion score < 2 (the nasal passage allows almost normal breathing at rest)

Visual analog scale total symptoms < 5

SNOT-22 value < 30

Chronic rhinosinusitis with nasal polys (CRSwNP) should not currently require the administration of systemic glucocorticosteroids or surgery for CRSwNP (except surgery to remove mechanical obstructions such as synechiae, mucoceles, etc.).