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. Author manuscript; available in PMC: 2024 Mar 28.
Published in final edited form as: Eur Neuropsychopharmacol. 2017 Nov 23;30:44–55. doi: 10.1016/j.euroneuro.2017.11.012

Table 1.

Suggestive associations in the RBFOX1 gene identified in GWAS of aggressive behaviors.

SNP Reference (GWAS) Chr bp (GRCh38) Alleles& MAF* Phenotype associated Sample P-value Risk allele
rs6500744 Sonuga-Barke et al., 2008 16 6063660 C>T 0.46 Conduct disorder symptoms interacting with mother’s warmth 938 trios 3.65 e-05 C
rs8062784 Merjonen et al., 2011 16 6096633 A>T 0.085 Anger (mean of 4 measurement phases) 2,242 adults 2.34 e-05 A
rs809682 Pappa et al., 2016 16 6346372 T>A 0.26 Children’s aggressive behavior 18,988 children 2.62 e-04 T
rs12922093 Pappa et al., 2016 16 6346947 T>C 0.26 Children’s aggressive behavior 18,988 children 3.21 e-04 T
rs12373031 Pappa et al., 2016 16 6347436 T>C 0.14 Children’s aggressive behavior 18,988 children 4.93 e-04 T
rs10521042 Pappa et al., 2016 16 6349836 C>T 0.14 Children’s aggressive behavior 18,988 children 4.35 e-04 C
rs12921846 Anney et al., 2008 16 6860384 A>T 0.16 Conduct disorder 938 trios 1.39 e-05 A
rs10153149 Anney et al., 2008 16 6875239 A>C 0.16 Conduct disorder 938 trios 3.64 e-05 A
&

According to the forward strand.

*

Minimum allele frequency in the European population from 1000 Genomes (http://www.internationalgenome.org/).