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. 2024 Mar 4;16(3):399. doi: 10.3390/v16030399

Table 1.

Number of clinical trials, cohort studies, and cross-sectional studies belonging to each of the six clinical scenarios.

Clinical Scenario ART
History
Viral Load
Prior to DTG
DTG-Containing
ART
Clinical Trials
(Number Trials)
Clinical Trials
(Number PLWH)
Cohort Studies
(Number Studies)
Cohort Studies
(Number PLWH)
Cross-Sectional Studies
(Number Studies)
Cross-Sectional Studies
(Number PLWH)
1 Naïve Viremic DTG + 2 NRTIs 16 4585 7 2698 1 113
2 Naïve Viremic DTG + 3TC 4 1075 3 581 0 0
3 Experienced Viremic DTG + 2 NRTIs 6 1428 5 3630 4 218
4 Experienced Suppressed DTG + 2 NRTIs 3 877 3 2204 0 0
5 Experienced Suppressed DTG + 2nd ARV 10 1894 18 5930 0 0
6 Experienced Suppressed DTG monotherapy 4 276 3 123 0 0

Abbreviations: ARV—antiretroviral; ART—antiretroviral therapy; DTG—dolutegravir; PLWH—people living with HIV.