Skip to main content
. Author manuscript; available in PMC: 2024 Mar 28.
Published in final edited form as: Nature. 2023 Jun 21;619(7970):624–631. doi: 10.1038/s41586-023-06234-x

Extended Data Fig. 4 |. Increased lymphocyte activation in Y+ tumors.

Extended Data Fig. 4 |

a, Volcano plot of DEGs from bulk RNA isolated from Y+ and Y− MB49 tumors grown in male WT mice. Blue (Y+ tumors) and red (Y− tumors) genes correspond to statistically significant (Benjamini-Hochberg method, P < 0.05) genes that have a | >1 log2 | fold-change in expression. b, PCA of DEGs described in a. c, Gene ontology (GO) pathway enrichment score plots of statistically significant gene set enrichment analyses (GSEA) using DEGs from a. NES, normalized enrichment score.