Figure 7.

Serum PRRSV-1 07V063 viral load, quantified by RT-qPCR, in piglets originating from routinely PRRSV vaccinated, seropositive sows (E+ piglets), or piglets originating from routinely PRRSV vaccinated, seronegative/slightly seropositive sows (E− piglets). Piglets were either non-vaccinated (NoVac), intramuscular vaccinated (IM), or intradermal vaccinated (ID) at 3 weeks of age with the same PRRSV-1 MLV as used in the sows. All piglets were intranasally challenged with the PRRSV-1 07V063 strain at 6 weeks of age. Dots represent the area under the curve (AUC) value for serum viral load, which was calculated from the day of infection (day 0) to 41 days post-infection (dpi) for each piglet. The mean AUC value ± standard error of the mean AUC value are shown as error bars. (A) AUC values for the E+ NoVac, E+ IM, E+ ID, E− NoVac, E− IM, and E− ID piglets. (B) AUC values for the E+ subgroups based on the vaccine antibody response. E+ responder piglets had a vaccine antibody response by 3 weeks post-vaccination, while the E+ non-responder piglets lacked a vaccine antibody response by 3 weeks post-vaccination. (C) AUC values for the E− subgroups based on the vaccine antibody response at 3 weeks post-vaccination.