Overview of interferon-γ secreting cells (IFN-γ SCs) specific for the PRRSV-1 DV strain in piglets originating from routinely PRRSV vaccinated, seropositive sows (E+ piglets) or piglets originating from routinely PRRSV vaccinated, seronegative/slightly seropositive sows (E− piglets) Piglets were either non-vaccinated (NoVac), intramuscularly vaccinated (IM) or intradermally vaccinated (ID) at 3 weeks of age with the same PRRSV-1 MLV as used in the sows. All piglets were intranasally challenged with the PRRSV-1 07V063 strain at 6 weeks of age. The number of PRRSV-specific IFN-γ SCs was quantified at 14, 21, 35, and 41 days post-infection (dpi). The mean number of IFN-γ SCs ± standard error of the mean are shown as error bars for each experimental group.