Figure 12.

Evolution of serum TNF-α in piglets originating from routinely PRRSV vaccinated, seropositive sows (E+ piglets) or piglets originating from routinely PRRSV vaccinated, seronegative/slightly seropositive sows (E− piglets). Piglets were either non-vaccinated (NoVac), intramuscularly vaccinated (IM), or intradermally vaccinated (ID) at 3 weeks of age with the same PRRSV-1 MLV as used in the sows, and all piglets were intranasally challenged with the PRRSV-1 07V063 strain at 6 weeks of age. The serum concentration of TNF-α was determined at 7, 10, 14, and 21 days post-infection (DPI) using a commercial ELISA assay. Results are shown as dots for each piglet, with error bars representing the mean concentration of serum TNF-α ± standard error of the mean concentration of serum TNF-α for each experimental group.