Fig. 5. Cytoprotective and cytotoxic effect of compounds on SH-SY5Y cells. Cytotoxic activity after 48 h incubation with compounds 23, 25, 27, 28, 29 and donepezil, trolox, rasagiline at 10 μM, 20 μM, 30 μM, 50 μM and 100 μM on SH-SY5Y cells. *P < 0.05, **P < 0.01, ***P < 0.001 and ns = non-significant.