In vitro inhibition results of COX-2 and 5-LOX.

Entry	IC50 (μM) ± SEMa
	COX-2	5-LOX
23	14.38 ± 0.28	0.59 ± 0.08
25	0.74 ± 0.13	5.96 ± 0.19
26	2.19 ± 0.10	1.17 ± 0.07
28	10.44 ± 0.13	0.47 ± 0.04
Celecoxib	0.05 ± 0.01	—
Zileuton	—	0.575 ± 0.11

^aValues represent mean ± SEM; n = 3