Table 1.

Characteristics of spinal cord lesions in adrenoleukodystrophy

Axons and myelin	Axonal degeneration equal to or greater than myelin loss.
Oligodendrocytes	Reduced in number.
Astrocytes	Isomorphic astrogliosis without reactive astrocytes.
Macrophages	PAS-positive macrophages abundant in perivascular spaces.
Microglia	Numerous activated microglia.
T-lymphocytes	Sparsely present as perivascular infiltrates.

Summary of the results presented by Powers et al. (2000). The following commercial antibodies were used for the stainings: neurofilament (NF), proteolipid protein (PLP), amyloid precursor protein (APP), glial fibrillary acidic protein (GFAP) and the microglia-macrophage markers HAM-56, CD68, 25FD, Ricinus, Lysozyme and non-specific esterase