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. 2024 Mar 27;23:89. doi: 10.1186/s12936-023-04810-0

Table 1.

Country malaria treatment policy contexts and status of PDMC policy adoption

Uganda
Treatment policy

1st line treatment for uncomplicated malaria

  Artemether-lumefantrine (AL)

  Alternative 1st line treatment is Artesunate-amodiaquine (AS-AQ)

2nd line treatment for uncomplicated malaria

  Dihydroartemisinin-piperaquine (DP)

Severe malaria

a) At health facility level:

  IV artesunate

  Dihydroartemisinin-piperaquine to be administered at discharge

b) Pre-referral treatment at community and lower-level health facilities

  Rectal artesunate, then continue as in (a) above

PDMC policy adoption status MoH has recommended adoption of WHO guidelines on PDMC
Malawi
Treatment policy

1st line treatment for uncomplicated malaria

  Artemether-lumefantrine (AL)

  Dihydroartemisinin-piperaquine (DP) is set to replace AL as first line treatment but has not yet been rolled-out

2nd line treatment for uncomplicated malaria

  Artesunate-amodiaquine (AS-AQ)

Severe malaria

  IV artesunate

  Dihydroartemisinin-piperaquine to be administered at discharge

PDMC policy adoption status

Evidence has been presented to Technical Working Group (TWG) (including case management) and Malaria Advisory Committee

MoH has asked Health Service Delivery TWG to review results prior to giving policy approval

Kenya
Treatment policy

1st line treatment for uncomplicated malaria

  Artemether-lumefantrine (AL)

  No planned changes to first line treatment choice

2nd line treatment for uncomplicated malaria

  Dihydroartemisinin-piperaquine (DP)

Severe malaria

  IV artesunate

  Artemether-lumefantrine to be administered at discharge

PDMC policy adoption status

Policy adoption of PDMC has not yet been initiated

Stakeholder engagement has commenced

Benin
Treatment policy

1st line treatment for uncomplicated malaria

  Artemether-lumefantrine (AL)

  Dihydroartemisinin-piperaquine (DP) is used in private facilities but is not available in the public system

2nd line treatment for uncomplicated malaria

  Pyronaridine-artesunate (AP) but not yet in the supply chain

Severe malaria

  IV artesunate

  Artemether-lumefantrine to be administered at discharge

PDMC policy adoption status

Policy adoption of PDMC has not yet been initiated

Stakeholder engagement has commenced